Individually selenium and α-tocopherol showed a pivotal role in combating abiotic stresses in plants. However, there is no report on how selenium behaves in the presence or absence of α-tocopherol under salt stress in crop plants. With this view, the present study was undertaken to dissect the interaction between selenium and α-tocopherol on growth performance, carbon metabolism, and uptake of different ions in maize plants grown under salt stress. This study was conducted with surface-sterilized seeds of maize that were soaked in deionized water (control), selenium (0.5 µM), and/or α-tocopherol (200 ppm) for 12 h before sowing and different salt levels (0, 100, 150, and 200 mM) in the form of NaCl was created in soil. A sample of maize plants from each treatment was collected 40 days after sowing. The results revealed that salinity lowered the growth performance, chlorophyll content, insoluble sugar