To investigate the effects of Zingiber officinalis and Cyanodon dactylon supplementation on the growth performance and immune parameters of Macrobrachium rosenbergii juveniles, five experimental diets, including a control basal diet and four treated diets with 1.5 and 3% Z. officinalis ; 2 and 4% C. dactylon were prepared. Prawn fed with control and supplemented diet for five weeks. Growth and immune parameters were evaluated. Juveniles fed with Z. officinalis and C. dactylon showed significant increase in SGR, CF, WGR, LGR and FCR compared with those of control along the whole experiment. Prawn fed all doses of Z. officinalis and C. dactylon revealed significantly higher THC, HV, DHC, PR and PI as compared with control at 4 and 5 weeks. Histopathologically, hepatopancreas and stomach of juveniles fed with Z. officinalis and C. dactylon showed normal histological structure. The results indicated that Z. officinalis and C. dactylon inclusion with a basal diet had the potential to improve the growth and immune response of prawns.