| publication name | Synthesis of Some Azoles and Azines based based on quinoline -8-yloxy-acetohydraide |
|---|---|
| Authors | Abdelmetaal Abdelmged, Aly. A. Aly, M. S. Amine and Ahmed. A. Ghith |
| year | 2015 |
| keywords | quinoline, 8-yloxy acetohydrazide, quinoline-8-yloxy methyl oxadiazole acetohydrazide, pyrazole thiazole, oxazole, triazole, pyridazine, phthalazine, isatine and antimicrobial activity. |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
A new Azoles and Azines as pyrazole, thiazole, oxadiazole, triazole, pyridazine and phthalazine based on quinolone moiety efficiently synthesized via very simple and efficient chemical reactions of quinolone-8-yloxy acetohydrazide and quinolone-8-yloxy methyl oxadiazole acetohydrazide with electrophilic reagents in base medium using simple techniques and reagents. The structures of the new synthesized products were deduced based on their analytical, spectral data and by using the fragmentation pattern as a tool for supporting the chemical structure also, the biological activity of the synthesized compounds as antimicrobial and antifungal were screened