Banner

Dexmedetomidine versus Ketamine for the Prevention of Emergence Agitation in Pediatric: A Prospective, Randomized, and Controlled Clinical Trial

Open Journal of Anesthesiology • 2020
العودة
معلومات البحث
المؤلفون Elsayed Mohamed Abdelzaam*, Enas W. Mahdy
الكلمات المفتاحية Emergence Agitation, Ketamine, Dexmedetomidine
المجلة العلمية Open Journal of Anesthesiology
الناشر Not Available
المجلد Not Available
العدد Not Available
الصفحات Not Available
publication.type International
رابط البحث Not Available
المواد المرفقة Not Available
الملخص
Background: This study compares the effect of dexmedetomidine versus Ketamine
for the prevention of emergence agitation in children undergoing
general anaesthesia. Method: 75 Children are randomly allocated into three
groups. Group C: Were assigned to receive normal saline. Group K: Were assigned
to receive Ketamine 0.25 mg/kg. Group D: assigned to receive 0.25 ug
/kg of dexmedetomidine, before the end of surgery. Results: There was no
statistically significant difference in demographic data and intraoperative parameters
between the three groups. But as regards to time to discharge, there
was a significant difference between group C, group K and group D (group C
= 39.96 ± 2.84, group K = 37.28 ± 3.80, group D = 35.08 ± 3.36 and P value =
0.0002). FLACC scale was low after extubation, before leaving the operating
room and on arrival to PACU (small FLACC scale in group K, D than group
C). PAED scoreless in Group K and Group D than Group C (postoperative, at
10 minutes, 20 min, 30 min). Conclusion: Ketamine and dexmedetomidine
reduced the incidence and severity of emergence delirium effectively when
compared to normal saline, and the effects of dexmedetomidine being much
superior to Ketamine.