This study was a trial to evaluate the level of zinc and its effect on T tymphocyte function In chronic renal failure patients
associated with active schistosomaJ Infection This study Included
50 cases 20 patients with chronic renal failure under regular
hemodialysis and associated with active. schistosomal infection. 20
patients with chronic renal failure under regular hemodialysis and not
associated with schistosomal infection and 10 subjects as a control
group.
For each case of this study; full history, complete clinical examination
, rectal snip , blood urea. serum creatinine , serum zinc and T -
lymphocyte function were all done before and after 4 weeks Zinc supplementation
( 660 mg / day) .
The level of serum zinc was significantly decreased in both groups
as compared with the control group.
The level of serum zinc in patients was not significantly higher after
than before zinc supplenentation .
There was non - significant increase of E - rosette percentage after
zinc supplementation for both groups .
There was non - significant increase of Blastoid transformation percentage
after zinc supplementation for both groups. We may conclude
that zinc supplemenation for periods more than 4 weeks is of benefit for
the level of serum zinc and T - lymphocyte function in patients with
chronic renal failure with schistosoma! infection