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Liquorice (Glycyrrhiza glabra) hydroethanolic extracts effectively alleviate Thioacetamide -induced hepatotoxicity and hematoxicity in experimental rats through their antioxidant nature
International Journal of Pharmacology and Toxicology (IJPT) • 2020
Publication Information
Authors
Alaa Behairy; Ashraf Elkomy;Faten Elsayed
Keywords
Hematotoxicity;Hepatotoxicity;Liquorice Extract;Rats;Thioacetamide.
Journal
International Journal of Pharmacology and Toxicology (IJPT)
Publisher
Alaa Behairy
Volume
9
Issue
(1)(2021)
Pages
10-16
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
Background: Liquorice (Glycyrrhiza glabra) is a high valued plant and used in a lot of countries around the world. The liquorice (LQ) has a remarkable medicinal, nutritional and socio-economic value. Therefore this study was designed to clarify the protective effect of liquorice hydroethanolic extract against Thioacetamide (TAA) induced hepatotoxicity and hematotoxicity in rats.
Materials and Methods: Seventy white Albino male rats were used in this study and after acclimatization rats were subjected to different treatments blood and tissue samples were collected after day 30 post administration, biochemical, antioxidant, hematological and histopathological examinations were utilized to investigate hepatoprotective activity of liquorice hydroethanolic extract.
Results: TAA significant (P
Materials and Methods: Seventy white Albino male rats were used in this study and after acclimatization rats were subjected to different treatments blood and tissue samples were collected after day 30 post administration, biochemical, antioxidant, hematological and histopathological examinations were utilized to investigate hepatoprotective activity of liquorice hydroethanolic extract.
Results: TAA significant (P