| publication name | Modified spectrophotometric method for the determination of some important antibiotics through charge-transfer complexatioin reaction with chloranil. |
|---|---|
| Authors | Alaa S. Amin, |
| year | 1996 |
| keywords | |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
A new modified Spectrophotometric procedures are presented for the determination of three pharmaceutical antibiotic compounds through charge-transfere complexation reaction with chloranil. The complex shows an absorption mAxima at 550 nm, having a molar absorptivity coefficient of 5.55×10,7.81×10 and 1.38×10 1. molcm for ampicillin, amoxycillin and neomycin, respectively. Optimization of the reaction conditions has been investigated Obediance to Beer's law (40μg/ml) permitted the assay of thes drugs in its dosage forms A variety of pharmaceutical dosage forms containing ampicillin, amoxycillin and neomycin are successfully analysed by the proposed procedure.