In spite of the evidence suggesting that many cannabinoid addicts are victims of infertility, yet there is little information about the extent of fertility affection and whether it is uniform on all fertility parameters or not. In order to clarify these issues, the effects of acute and chronic cannabinoid agonist (bango) inhalation on different semen parameters, serum gonadotrophins, prolactin levels and testicular functions were studied. The results of this study revealed that acute bango inhalation resulted in a statistically significant reduction in sperm viability (p< 0.05) and motility (p