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Treating vestibular schwannomas with Gamma-knife radiosurgery versus microsurgery: long-term follow-up of 702 cases

• 2019
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Publication Information
Authors Ahmed R. Rizk3, Gerhard Alfons Horstmann2, Marcos Tatagiba1
Keywords vestibular schwannoma, radiosurgery, microsurgery, gamma knife.
Journal Not Available
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publication.type Local
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Background: The three treatment options currently considered for vestibular schwannoma are expectant treatment, microsurgery and radiosurgey, and to date no class I evidence favors one treatment over the others.
Aim of the study: The objective of this study was to compare long-term functional outcome after gamma knife radiosurgery versus surgical treatment.
Methods: A group of 275 patients submitted to microsurgery and 427 patients treated with radiosurgery in two different centers were followed-up for 15.2 ± 13.6 months and 45.6 ± 26.8 months, respectively. We assessed tumor volumetry based on serial MR images, facial nerve function, hearing function, tinnitus, trigeminal symptoms and vertigo, and compared them between treatment groups.
Results: Based on normalized volumetry over time, surgery was more efficient for tumor control than radiosurgery (p