Normal Reference ranges for Fetal cardiac function: Assessed by modified Doppler myocardial performance index (Mod MPI) in the Egyptian population
European Journal of Obstetrics & Gynecology and Reproductive Biology • 2020
Publication Information
Authors
Sief Ali, Ahmed Okasha, Sherif Elsirgany, Ahmed Khalil, Sherif El-Anwary, Ahmad Elsheikhah
Keywords
Modified Doppler myocardial performance index
MOD MPI
Fetal cardiac function
Tie index
Journal
European Journal of Obstetrics & Gynecology and Reproductive Biology
Publisher
elsevier
Volume
251
Issue
Not Available
Pages
66-72
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Objective: To develop gestational age-based reference ranges for the modified Doppler myocardial performance index (Mod MPI) and to examine the maternal characteristics that affect this measurement.
Study design: This was a cross-sectional study, comprised of 1021 healthy pregnancies between 20+0 to 35+6 weeks' gestation. They were all undergoing ultrasound examination in Cairo Fetal Medicine Unit (CAIFM) in Cairo University, Egypt from 1ST April 2017 till 1st April 2019. Mod MPI was obtained used method described by Friedman et al 2003.
Median and SD models were fitted between Mod MPI and gestational age. The distributions of Mod MPI Z-scores were examined in relation to maternal characteristics
Results: The normal Mod MPI in second and third trimester (20+1 - 35+6 weeks' gestation) was 0.408 ± 0.08. Mod MPI was not affected by maternal age, body mass index (BMI) or parity (p value 0.5, 0.6 and 0.2 respectively).
Conclusion: This study established normal reference ranges for Mod MPI according to gestational age and generated a graph with 5th,10th, 90th and 95th centiles. Maternal characteristics as age, BMI or parity do not affect value of Mod MPI.
Study design: This was a cross-sectional study, comprised of 1021 healthy pregnancies between 20+0 to 35+6 weeks' gestation. They were all undergoing ultrasound examination in Cairo Fetal Medicine Unit (CAIFM) in Cairo University, Egypt from 1ST April 2017 till 1st April 2019. Mod MPI was obtained used method described by Friedman et al 2003.
Median and SD models were fitted between Mod MPI and gestational age. The distributions of Mod MPI Z-scores were examined in relation to maternal characteristics
Results: The normal Mod MPI in second and third trimester (20+1 - 35+6 weeks' gestation) was 0.408 ± 0.08. Mod MPI was not affected by maternal age, body mass index (BMI) or parity (p value 0.5, 0.6 and 0.2 respectively).
Conclusion: This study established normal reference ranges for Mod MPI according to gestational age and generated a graph with 5th,10th, 90th and 95th centiles. Maternal characteristics as age, BMI or parity do not affect value of Mod MPI.
Staff Members - Benha University