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Folic Acid Intake and Neural Tube Defects: Two Egyptian Centers Experience

Medicine  Volume 94, Number 37, September 2015 www.md-journal.com | 1 • 2015
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Authors Mortada H. El-Shabrawi, MD, Naglaa Mohamed Kamal, MD, Mona Abbas Elhusseini, MD, Laila Hussein, MD, Enas Abdallah Ali Abdallah, MD, Yahia Zakaria Abdelalim Ali, MD, Ahmed Abelfattah Azab, MD, Mostafa Abdelazim Salama, MD, Muna Kassab, MD, and Michael Kr
Keywords Medicine  Volume 94, Number 37, September 2015 www.md-journal.com | 1
Journal Medicine  Volume 94, Number 37, September 2015 www.md-journal.com | 1
Publisher Medicine  Volume 94, Number 37, September 2015 www.md-journal.com | 1
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publication.type International
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Abstract
Abstract: Neural tube defects (NTDs) are a group of congenital
malformations with worldwide distribution and complex etiopathogenesis.
Folic acid plays a pivotal role in their prevention. We aimed to
identify the protective effect of folic acid intake against NTDs and its
dependence on different socioeconomic and environmental factors in a
cohort of mothers in Egypt.
A cross-sectional study was carried over a period of 12 months on
mothers who gave birth to babies with NTDs (group 1) and a control
group with healthy offsprings (group 2). Both groups completed 2
questionnaires: food frequency questionnaire targeting the daily folate
intake, and socioeconomic status and medical history questionnaire.
Both groups of mothers received folate