Staff Members - Benha University
Serum procalcitonin level may predict AKI in ICU patients with sepsis
• 2017
Publication Information
Authors
Mahmoud H. Imam,1 Enas Elsebaey Ahmed,3 Amr Marzouk,2 Amira Mohamady,3, Rizk Sayed
Rizk Sarhan,3 Ahmed W. Elshourbagy.4
Keywords
Not Available
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Background: Sepsis still has a high incidence even in developed countries. Acute
kidney injury (AKI) frequently occurs in significant percentage of septic ICU critically ill
patients with decimal prognosis. Early prediction of AKI and early interventions may
improve outcome. The aim of this study is to examine if procalcitonin (PCT) can be used
for early prediction AKI septic patients in ICU. Methods: 67 patients with sepsis were
enrolled in this study. On admission, PCT was measured together with serum creatinine,
urea, and other inflammatory markers. qSOFA was calculated at the emergency
department. Patients were classified into two groups: AKI and non-AKI groups. Results:
PCT had a significantly higher value among patients who developed AKI than non-AKI
group (67.04±20.59 ng/ml vs. 36.84±18.36 ng/ml); p < 0.001. Also, PCT exhibited a
good predictive role for AKI with the ROC area under the curve was. 0859 (p < 0.001).
Conclusions: PCT may help in the early prediction of AKI among septic ICU patients.
kidney injury (AKI) frequently occurs in significant percentage of septic ICU critically ill
patients with decimal prognosis. Early prediction of AKI and early interventions may
improve outcome. The aim of this study is to examine if procalcitonin (PCT) can be used
for early prediction AKI septic patients in ICU. Methods: 67 patients with sepsis were
enrolled in this study. On admission, PCT was measured together with serum creatinine,
urea, and other inflammatory markers. qSOFA was calculated at the emergency
department. Patients were classified into two groups: AKI and non-AKI groups. Results:
PCT had a significantly higher value among patients who developed AKI than non-AKI
group (67.04±20.59 ng/ml vs. 36.84±18.36 ng/ml); p < 0.001. Also, PCT exhibited a
good predictive role for AKI with the ROC area under the curve was. 0859 (p < 0.001).
Conclusions: PCT may help in the early prediction of AKI among septic ICU patients.