Staff Members - Benha University
Endothelial dysfunction marker YKL-40 is elevated in male patients with idiopathic infertility
Andrologia • 2018
Publication Information
Authors
SM Hanafy; HH Sabry; JH Sabry; AM Hamed
Keywords
endothlial dysfunction; infertility; metabolic syndrome YKL-40
Journal
Andrologia
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
Ahmed Mohamed Hamed Mahmod_ykl in infertility.pdf
Abstract
Summary
Metabolic syndrome represents a collection of cardiovascular risk factors, including
overweight, hypertension, dyslipidemia and impaired glucose metabolism, with insulin
resistance. In recent years, the potential relationship between metabolic syndrome
and male factor infertility has been studied. As endothelial dysfunction is the hallmark
of metabolic syndrome, the aim of this work was to assess serum levels of YKL-40
as
a marker of endothelial dysfunction in male patients with idiopathic infertility. The
study revealed that YKL-40
levels were elevated in patients than controls denoting
that endothelial dysfunction might play a role in the pathogenesis of idiopathic infertility
and that YKL-40
as a marker of endothelial dysfunction could be a useful marker of idiopathic infertility.
Metabolic syndrome represents a collection of cardiovascular risk factors, including
overweight, hypertension, dyslipidemia and impaired glucose metabolism, with insulin
resistance. In recent years, the potential relationship between metabolic syndrome
and male factor infertility has been studied. As endothelial dysfunction is the hallmark
of metabolic syndrome, the aim of this work was to assess serum levels of YKL-40
as
a marker of endothelial dysfunction in male patients with idiopathic infertility. The
study revealed that YKL-40
levels were elevated in patients than controls denoting
that endothelial dysfunction might play a role in the pathogenesis of idiopathic infertility
and that YKL-40
as a marker of endothelial dysfunction could be a useful marker of idiopathic infertility.