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Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of Keratoconus

Journal of Ophthalmology • 2018
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Publication Information
Authors Mohammed Iqbal Hafez Saleem ,1 Hosam A. Ibrahim Elzembely,2 Mortada Ahmed AboZaid,1 Mohammed Elagouz ,1 Ahmed Mohamed Saeed,3 Osama Ali Mohammed,1 and Ahmed Gad Kamel1
Keywords Not Available
Journal Journal of Ophthalmology
Publisher hindawi
Volume Not Available
Issue Not Available
Pages Not Available
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Purpose. To analyze the results of three-year outcomes of combined epithelium-on cross-linking with femtosecond laser ICRS
(cross-linking PLUS) for keratoconus management. Design. A retrospective multicenter clinical study. Methods. 43 eyes of 38
patients were subjected to preoperative and postoperative UCVA, BCVA, refraction, Pentacam pachymetry, and keratometry
examinations at 3-, 6-, 12-, 24-, and 36-month follow-up period. Results. The preoperative and postoperative mean UCVA was
1.30 ± 0.48 (logMAR ± SD) and 0.82 ± 0.22 respectively. The preoperative and postoperative mean BCVA was 0.90 ± 0.40 and
0.60 ± 0.30, respectively. The preoperative and postoperative mean K average was 50.63 ± 0.87 (D ± SD) and 45.56 ± 0.98,
respectively. The preoperative and postoperative mean pachymetry was 471 ± 92.36 (μm± SD) and 423 ± 39.58, respectively.
The preoperative and postoperative mean astigmatism was 7.55 ± 1.75 and 3.39 ± 1.26, respectively. One eye showed ICRS
edge exposure while 6 eyes showed progression of keratoconus. Conclusion. CXL PLUS was proved to be a successful
procedure to halt progression (mainly by CXL) and to correct the refractive status of the keratoconic eye (mainly by ICRS).
CXL PLUS performed a synergistic action correcting and maintaining the correction of both myopic and astigmatic components
of keratoconus.