• Hereditary haemorrhagic telangiectasia is a relatively common vasculopathy, more than 90% of patients develop epistaxis. • Septal dermoplasty procedures yielded successful results in reducing epistaxis but also resulted in the destruction of the nasal mucosa. Therefore, it seems that the ideal treatment is to replace the diseased nasal mucosa with healthy nasal mucosa. • In this study, the mucosa from the posterior inferior turbinate was used to replace the telangiectic area on the nasal septum in 16 patients along with radiofrequency coagulation on other areas. • The frequency and intensity of epistaxis were graded into three categories and were used to compare preand postoperative severity where grade I is the least in severity. • Preoperative grade I frequency included two patients and preoperative grade I intensity included one patient. Postoperative grade I frequency and intensity included 12 and 13 patients, respectively. There were no cases of graft rejection, septal perforation or atrophic rhinitis.