Background:Patent ductus arteriosus (PDA)can be treated by transcatheter device closure . This study is our experience in Tanta and Benha University Hospitals Aim: Initial experience with transcatheter closure of (PDA) using different types of devices .To evaluate the feasibility , efficacyand safety of transcatheter closure of PDA in pediatric age group patients on basis of short-term follow upPatients & Methods:This prospective observational studyincluded 26 childrenwith PDA; 21 female and 5 males with age 30.2 ± 27.6 months, weight12.8 ± 6.6 Kg and body surface area 0.54 ± 0.2m2. Aortic angiogram was performed to evaluatethe duct sizeand shape for appropriately choosing the occluder type andsize. A second aortic angiogram was performed 10 min after device deployment. Every patient had echocardiographic assessment before and after ductus closure. Follow up was done 24 hour, 1 week and 3 months post-intervention. Evalution included immediate and remote complications, residual shunt, Left ventricle dimensions, left atrium / aorta ratio and pressure gradient along descendingaortaand left pulmonary artery.Results: No complications like thrombus formation, blood loss or infective endocarditis in any casewerereported after successful ducts closure.Completeductus closure was achieved in 77%of cases by 24 hours post-intevension, andin 96.15 %after three months. The left side dimensions had significantly decreased ; the left ventricular end diastolic diameter (LVEDd) decreased from 33.28±4.92mm pre-interventionto 26.54±4.53 after 3 months (P