Out of 50 samples were taken from each carcasses surfaces of camel, cattle, sheep and goat from Kalyobia abattoirs, the minimum number/cm² of Escherichia coli strain isolated were 5.1X10², 3.7X10², 2.3X10², and 3.5X10², while the maximum numbers were 3.5X 105, 4.5X104, 1.3X104, and 5.1X104, With means of 3.2X104, 6.1X10³, 4.3X10³, and 9.7X10³, respectively. The incidence rate of enterohaemorragic Escherichia coli for the Strain O26: K66 (B6), was 6% ,2%,14% and 2% respectively. While for the strain O111: K58 was 2%,14%,6 %and 10% respectively. While for the strain O157 was 6%,4%,10% and 6% respectively. The incidence rate of enteroinfectious Escherichia coli strains for the Strain O124: K72 was 4%,2%,10% and 0% respectively. The incidence rate of enterotoxogenic Escherichia coli strains for the Strain O128: K67 (B12) was 2%,16%,6% and 10% respectively. The incidence rate of enteropathogenic Escherichia coli for the strain O55: K59 (B5), was 14%,6, %16% and 10 %respectively. While for the strain O119: K69 (B14) was 6%,2%,2% and 2% respectively. While for the strain O126: K71 (B16) was 4%,12%,6% and 8% , respectively. While for the strain O142: K86 was 4%,12%,6% and 8% respectively. While for the strain O44: K74 (L) was 6%, 2%,8 %and 4%respectively. While for the strain O114: K90 (B) was 2%,10%,2% and 2% respectively. The incidence rate of some other serotypes of Escherichia coli for the strains O86: K61 (B7), which was 2%,4%,8% and 0% respectively. While for the strain O112: K66 (B11) was 10%,2%,0 %and 6% respectively. While for the strain O127: K63 (B17) was 4%,0%, 2% and 10% respectively. The incidence rate of enteroinfectious Escherichia coli strain out of 50 samples taken from the diarrheic man in the same localities of animals, 33 cases were positive with percentage 66%. Two types were isolated from diarrheic man O127: K63 (B17) and O157 Escherichia coli strains with incidence rate 28%, 42% respectively. The effect of three different disinfectants on to three different human strains of enterohaemorrhagic Escherichia coli strains O157, O111: K58 (B4) and O26: K66 (B6) revealed the most effective disinfectant in different dilutions was Betidin then formalin while Pot. Permanganate was with moderate effect.