Staff Members - Benha University
Telomere Length Measurement by Quantitative Real-time PCR: A Molecular Marker for Human Age Prediction
American Journal of Biochemistry and Biotechnology • 2016
Publication Information
Authors
Naglaa F. Alhusseini andAbdelmonem G. Madboly
Keywords
Telomere Length, Molecular Marker, Human Age Prediction,
Quantitative Real-Time PCR, Egyptians
Journal
American Journal of Biochemistry and Biotechnology
Publisher
science puplications
Volume
12
Issue
(1)
Pages
64.71
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
Abstract: The fact that telomere shortening occurs with aging leads to the
hypothesis that a correlation could be made between Telomere Length (TL)
and suspect age. This study aimed to assess if TL can be used as an
investigational tool to predict human age through developing a formula
based on this correlation with accuracy suitable to be applied in forensic
practice. A quantitative real-time PCR study was carried out on 80
Egyptians, ranging in age from 1-79 years. The results confirmed that the
relative TL significantly shortened with aging; “r” = -0.903 (p
hypothesis that a correlation could be made between Telomere Length (TL)
and suspect age. This study aimed to assess if TL can be used as an
investigational tool to predict human age through developing a formula
based on this correlation with accuracy suitable to be applied in forensic
practice. A quantitative real-time PCR study was carried out on 80
Egyptians, ranging in age from 1-79 years. The results confirmed that the
relative TL significantly shortened with aging; “r” = -0.903 (p