| publication name | Telomere Length Measurement by Quantitative Real-time PCR: A Molecular Marker for Human Age Prediction |
|---|---|
| Authors | Naglaa F. Alhusseini andAbdelmonem G. Madboly |
| year | 2016 |
| keywords | Telomere Length, Molecular Marker, Human Age Prediction, Quantitative Real-Time PCR, Egyptians |
| journal | American Journal of Biochemistry and Biotechnology |
| volume | 12 |
| issue | (1) |
| pages | 64.71 |
| publisher | science puplications |
| Local/International | International |
| Paper Link | https://thescipub.com/abstract/10.3844/ajbbsp.2016.64.71 |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Abstract: The fact that telomere shortening occurs with aging leads to the hypothesis that a correlation could be made between Telomere Length (TL) and suspect age. This study aimed to assess if TL can be used as an investigational tool to predict human age through developing a formula based on this correlation with accuracy suitable to be applied in forensic practice. A quantitative real-time PCR study was carried out on 80 Egyptians, ranging in age from 1-79 years. The results confirmed that the relative TL significantly shortened with aging; “r” = -0.903 (p