A circularly polarized (CP) multi-input multioutput (MIMO) dielectric resonator (DR) antenna (DRA) with compact size and four ports is implemented. CP radiation was achieved using the deformed DR geometry excited with aperture coupled feeding. A CPDRA with a single and two ports is investigated. The defected ground structure (DGS) was incorporated into the antenna for improving the isolation between the ports. The DGS was incorporated in such a way that the required phase difference between the generated orthogonal degenerate modes is preserved. This concept could be utilized in implementing a compact four-port CP antenna. The MIMO antenna provides a 10 dB impedance bandwidth of 38% (8.5–12.5 GHz) and a 3 dB AR bandwidth of 9.32% (9.2–10.1 GHz). The gain of the implemented antenna was around 6 dBi in the band where CP radiation was achieved. The MIMO performance parameters were calculated, and their values remained within the acceptable limits. The implemented antenna could suitably be used in X-band applications.