Static light scattering from an aqueous solution of Pluronic F-108 prill has been measured over the angles range (40o to 140o ) for four different concentrations (0.004, 0.006, 0,008, 0.01 gm/ml). A home build multiangle static light scattering experiment was used to calculate the Rayleigh ratio and construct the Zimm plot, which was used to calculate the radius of gyration〈 〉, the second virial coefficient A2, and the molecular weight . The refractive index was measured by abbe's refractometer to calculate refractive index increment . The measured data show that the molecular weight of Pluronic F-108 prill is 14661 gm/mole, which is a medium molecular weight. The second viral coefficient is greater than zero, which means that the Pluronic F-108 prill likes the solvent (deionized water) more than itself. While the radius of gyration 〈 〉 is 1094 nm, which is a little bit large as in an aqueous environment these block copolymers self-assemble into micelles