This work aimed to evaluate the hepatoprotective effect of garlic oil extract with regarding to clinical, hematobiochemical alteration and oxidative stress status of induced acute hepatopathy in Baladi goats. Ten Baladi goats were kept for experimental induction of hepatopathy that treated orally with 0.3 ml /kg of carbon tetrachloride (CCL4)once and divided randomly into two groups each of five. Group A was kept as control positive. Group B was treated by garlic oil extract in dose 0.8g/kg for 15 days for hepatic protection before induction. Clinical and hematobiochemical examination were carried out at 1st, 3rd and 7th day after induction. Clinical examinations of CCl4 treated group at first day showed dullness, inappetence, pale mucous membranes, elevated body temperature and pulse rate and nervous manifestations. While garlic oil treated group showed less severe clinical signs that began to disappear at 3rd day after induction. Hematobiochemical examination: induced acute hepatopathy group showed significant (P