Purposes: Find out advantages & efficacy of Platelet Rich Plasma versus conventional ordinary dressing in management of diabetic foot ulcer & wound. Background: Diabetic foot ulcer treatment places a considerable strain on the medical system, with long waiting time for healing in the public hospital system. Platelet Rich Plasma allows efficient treatment of many patients with hemostatic, anti-inflammatory and analgesic substance. Patients and methods: This prospective randomized controlled study was conducted on 60 diabetic patients having non-healing feet ulcers; Patients were randomly allocated by using a computer generated random number table into two groups according to the dressing method performed; Group A: Conventional ordinary dressing (N=30 (50%)), Group B: PRP dressing (N=30 (50%)). Follow-up period was for 3-monthes. Results: Most of ulcers were healed within the estimated time for this study (12 weeks) and There were satisfactory results (less complications) in PRP group (B); infection, exudates and Pain which were observed in 5 cases (16%), 3 cases (10%), 10 cases (33.3%) respectively as compared to group (A); 8 cases (26.6%), 12 cases (40%), 18 cases (60%) respectively. Also the rate of healing was good in group (B) with p-value