Background: Preterm premature rupture of membranes is a frequent every day obstetric clinical scenario the proper line of
management is considered lifesaving in some situations. The main aim of most investigators and practitioners all over the globe is
to explore the safest management line according to the pros and cons of each decision.
Aim: To compare the neonatal clinical outcomes of cases women having PPROM before 34 gestational weeks, in accordance to
the management protocol (inpatient versus outpatient care).
Methodology: A prospective clinical research trial that recruited 300 research study subjects Inclusive research criteria were
admitted with a clinical diagnosis of PPROM between 24+0 and 33+6 gestational weeks and didn’t deliver within the 48 hours after
PPROM. Exclusive research criteria have been twin gestations, fetal anomalies.
Results: The statistical Logistic regression analysis for factors associated to outpatient delivery showing that there was statistical
significance concerning Tocolysis, Hospital length of stay > 13 days, Cesarean section, Composite perinatal outcome measure, Cord
prolapse, Maternal hospital stay > 4 days (p values < 0.001, 0.020, 0.037, 0.049, 0.047 consecutively).
Conclusion: Outpatient care of PPROM clinical scenarios is considered a safe effective alternative traditional inpatient
management line, however future research efforts are required to be conducted in a multicentric fashion with larger sample sizes
to aid in future implementation of the best clinical management guidelines.