Staff Members - Benha University
Gender specific clinical indicators of congestive heart failure in the middle east: Data from a single centre heart failure registry
European Journal of Heart Failure Abstracts Supplement • 2016
Publication Information
Authors
K Salem , D Fallata , K Sheeren , O Elkhateeb
Keywords
Not Available
Journal
European Journal of Heart Failure Abstracts Supplement
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
Shereen Mohamed Khalid_Abstract_P1473.pdf
Abstract
Background/Introduction: Clinical outcome measures are the mainstay of cardiology trials. Congestive heart
failure (CHF) measures have traditionally focused on average length of stay (LOS) and rehospitalisation and
mortality rates. Purpose: We aimed to identify the significant factors of gender variability of CHF patients with
a reduced ejection fraction (HFrEF). Methods: We performed gender comparison of statistically relevant
variables using prospectively collected data of HFrEF patients hospitalised over a 12month
period. Results:
Of 174 consecutive patients, 135 (78%) were males and 39 (22%) were females. Compared to males, females
had a statistically significant older age (64 vs. 58; P < 0.001), higher ejection fraction (EF) (28% vs. 23%; P =
0.023) and no history of active smoking (0% vs. 16%; P = 0.005) and less use of beta blockers (76% vs. 93%;
P = 0.006), digitalis (2% vs. 12%; P = 0.009) and mineralocorticoid receptor antagonist drugs (35% vs. 55%;
P = 0.025). After one year, both males and females had similar allcause
and heart failure hospitalisation and rehospitalisation
rates. Females showed no differences in inhouse
mortality, combined inhouse
mortality/30day
rehospitalisation
rates and composite myocardial infarction/stroke rates, compared to males. Males were more
likely to require defibrillator device implantation (34% vs. 12%; P = 0.008) Conclusion: Our findings showed
that female HFrEF patients had similar LOS; inhouse
mortality, hospitalisation and rehospitalisation rates; less
utilisation for implantable devices.
failure (CHF) measures have traditionally focused on average length of stay (LOS) and rehospitalisation and
mortality rates. Purpose: We aimed to identify the significant factors of gender variability of CHF patients with
a reduced ejection fraction (HFrEF). Methods: We performed gender comparison of statistically relevant
variables using prospectively collected data of HFrEF patients hospitalised over a 12month
period. Results:
Of 174 consecutive patients, 135 (78%) were males and 39 (22%) were females. Compared to males, females
had a statistically significant older age (64 vs. 58; P < 0.001), higher ejection fraction (EF) (28% vs. 23%; P =
0.023) and no history of active smoking (0% vs. 16%; P = 0.005) and less use of beta blockers (76% vs. 93%;
P = 0.006), digitalis (2% vs. 12%; P = 0.009) and mineralocorticoid receptor antagonist drugs (35% vs. 55%;
P = 0.025). After one year, both males and females had similar allcause
and heart failure hospitalisation and rehospitalisation
rates. Females showed no differences in inhouse
mortality, combined inhouse
mortality/30day
rehospitalisation
rates and composite myocardial infarction/stroke rates, compared to males. Males were more
likely to require defibrillator device implantation (34% vs. 12%; P = 0.008) Conclusion: Our findings showed
that female HFrEF patients had similar LOS; inhouse
mortality, hospitalisation and rehospitalisation rates; less
utilisation for implantable devices.