Staff Members - Benha University
Evaluation of cross-protection between FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines by challenge test.
• 2015
Publication Information
Authors
Gabr. F. El-Bagoury1
, Saad. S.A Sharawi1
, Ehab. M. El-Nahas1
, Darwish. M. Darwish2
,
Mohammed. A. Saad.
Keywords
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Journal
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Publisher
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Volume
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Issue
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Pages
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publication.type
Local
Paper Link
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Supplementary Materials
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Abstract
Foot-and-mouth disease (FMD) is a highly contagious and economically devastating viral disease of
cloven-hoofed animals. In Egypt, the local commercial (trivalent O Panasia-2/A Iran-05/ SAT2/EGYA-2012) and imported (trivalent O Manisa /A Iran-05/ SAT2/EGY-A-2012) inactivated vaccines were
used for rapid control of the disease. We aimed to determine the cross protection between FMD virus
serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported
vaccines using challenge experiment. By the 7th day post challenge with either O/EGY-4-2012 or
A/EGY/1/2012 isolates, the vaccinated cattle with either local commercial or imported vaccine were
clinically protected by 100% with local commercial vaccine and 80% with imported vaccine for O/EGY4-2012. The protection values were 100% and 80% with cattle challenged with A/EGY/1/2012 and
vaccinated with a local commercial or imported vaccine respectively. In conclusion, FMD virus
Egyptian isolates O and A was antigenically similar to that of vaccinal strains in local commercial and
imported vaccines which provide good protection.
cloven-hoofed animals. In Egypt, the local commercial (trivalent O Panasia-2/A Iran-05/ SAT2/EGYA-2012) and imported (trivalent O Manisa /A Iran-05/ SAT2/EGY-A-2012) inactivated vaccines were
used for rapid control of the disease. We aimed to determine the cross protection between FMD virus
serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported
vaccines using challenge experiment. By the 7th day post challenge with either O/EGY-4-2012 or
A/EGY/1/2012 isolates, the vaccinated cattle with either local commercial or imported vaccine were
clinically protected by 100% with local commercial vaccine and 80% with imported vaccine for O/EGY4-2012. The protection values were 100% and 80% with cattle challenged with A/EGY/1/2012 and
vaccinated with a local commercial or imported vaccine respectively. In conclusion, FMD virus
Egyptian isolates O and A was antigenically similar to that of vaccinal strains in local commercial and
imported vaccines which provide good protection.