Staff Members - Benha University
The Role of Arteriovenous Shunt on Increased Prevalence of Unexplained Pulmonary Hypertension in Hemodialysis Patients .
International Journal of Advanced Research • 2015
Publication Information
Authors
Mohamed A. Tabl MD1 , Mohamed H. Ibrahim MD1, EL Sayed M.Farag MD2, Ahmed Wageh MD3
Keywords
Pulmonary hypertension, Hemodialysis, Arterio-venous shunt
Journal
International Journal of Advanced Research
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
Background: recent studies have shown a high incidence of unexplained pulmonary hypertension (PHT) in end-stage renal disease (ESRD) patients with or without haemodialysis (HD) therapy. The aim of this study was to evaluate the prevalence of unexplained PHT among patients with ESRD on regular HD and possible role of arteriovenous (AV) shunt as an etiological factor.
Materials and methods: We enrolled 80 consecutive patients with ESRD on regular HD via AV shunt. Forty random chronic kidney disease (CKD) (predialysis) patients were taken up as a control. All patients underwent transthoracic echocardiography to assess the pulmonary artery pressure and cardiac output (CO). Pulmonary hypertension was defined as, pulmonary artery systolic pressure (PASP) greater than 35 mm Hg at rest. In HD patients with PHT, we reassessed CO and PASP before and after 1 minute of temporary compression over the AV shunt.
Results: Patients on HD had higher PASP in comparison to control group. Out of 80 HD patients studied, 16 patients (20%) had PHT (PASP = 46±2 mmHg) while the rest had a normal PASP (29±1 mmHg) (P
Materials and methods: We enrolled 80 consecutive patients with ESRD on regular HD via AV shunt. Forty random chronic kidney disease (CKD) (predialysis) patients were taken up as a control. All patients underwent transthoracic echocardiography to assess the pulmonary artery pressure and cardiac output (CO). Pulmonary hypertension was defined as, pulmonary artery systolic pressure (PASP) greater than 35 mm Hg at rest. In HD patients with PHT, we reassessed CO and PASP before and after 1 minute of temporary compression over the AV shunt.
Results: Patients on HD had higher PASP in comparison to control group. Out of 80 HD patients studied, 16 patients (20%) had PHT (PASP = 46±2 mmHg) while the rest had a normal PASP (29±1 mmHg) (P