Comparative Study Following Addition of Epinephrine (0.2mg) to Spinal Hyperbaric Bupivacine (0.5%) in Normotensive and PreEclamptic Parturients Undergoing Elective Cesarean Section: A Pilot Study
• 2020
Publication Information
Authors
Mohamed Fouad Mohamed Elmeleigy*
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publication.type
International
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Abstract
Introduction: Study compare effect of adding epinephrine to bupivacine-fentanyl mixture during spinal anesthesia for elective cesarean
section in normotensive and pre-eclamptic parturients.
Methods: Twenty parturients who had given their consent and were scheduled for elective cesarean section under spinal anesthesia, where
divided into four groups first group contain five normotensive parturients received 0.5% hyperbaric bupivacine plus fentanyl, the second group
also contain five normotensive parturients received 0.5% hyper bupivacaine-fentanyl mixture plus epinephrine (0.2mg), the third group contain
five severe pre-eclamptic parturients received hyperbaric bupivacine 0.5% plus fentanyl, the fourth group contain five severe pre-eclamptic
parturients received hyperbaric bupivacine- fentanyl mixture plus epinephrine (0.2mg). The hemodynamics, anesthesia characteristics and
adverse effects were observed.
Results: Mean heart rate didn’t significantly differ between groups either A, B or C and D. there is difference in percentage of drop of mean
blood pressure from baseline between group A, B (statistically significance) and drop in C, D (not statistically significance). The anesthesia onset
time for sensory block significantly (P=0.03) prolonged in group B than in group A (4.6±1.14 vs 2.8±0.84minute) and the same in group D than
group C (4.2±0.45 vs 2.8±0.45min) (P=0.005), the time of sensory block to regress below L1 was significantly (P
section in normotensive and pre-eclamptic parturients.
Methods: Twenty parturients who had given their consent and were scheduled for elective cesarean section under spinal anesthesia, where
divided into four groups first group contain five normotensive parturients received 0.5% hyperbaric bupivacine plus fentanyl, the second group
also contain five normotensive parturients received 0.5% hyper bupivacaine-fentanyl mixture plus epinephrine (0.2mg), the third group contain
five severe pre-eclamptic parturients received hyperbaric bupivacine 0.5% plus fentanyl, the fourth group contain five severe pre-eclamptic
parturients received hyperbaric bupivacine- fentanyl mixture plus epinephrine (0.2mg). The hemodynamics, anesthesia characteristics and
adverse effects were observed.
Results: Mean heart rate didn’t significantly differ between groups either A, B or C and D. there is difference in percentage of drop of mean
blood pressure from baseline between group A, B (statistically significance) and drop in C, D (not statistically significance). The anesthesia onset
time for sensory block significantly (P=0.03) prolonged in group B than in group A (4.6±1.14 vs 2.8±0.84minute) and the same in group D than
group C (4.2±0.45 vs 2.8±0.45min) (P=0.005), the time of sensory block to regress below L1 was significantly (P
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