Staff Members - Benha University
Effect of GABA on Hematological, Biochemical, Antioxidant and Immunological Parameters in Laying Hens
Advances in Pharmacology and Clinical Trials • 2019
Publication Information
Authors
Elkomy A, Zahra A, Belih S, Shaheen Y, Abugomaa A, Elbadawy M* and Aboubakr M*
Keywords
Antioxidant; Blood picture; Chickens; GABA; Layers; Immunity
Journal
Advances in Pharmacology and Clinical Trials
Publisher
Medwin Publishers
Volume
4
Issue
4
Pages
Article ID: 000170, 7 pages
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
The present work investigated the effect of GABA on hematological, biochemical, antioxidant and immunological
parameters in laying hens. Sixty Lohmann Brown laying hens (32 weeks old) were randomly allotted to 3 groups (each
20) and given the medications daily for 4 weeks in drinking water. The groups were; control (without drug), GABA (40
mg/kg b.wt) and GABA (80 mg/kg b.wt). Layers were estimated to complete blood picture, Hb, differential leucocytic
count, antioxidant parameters, cholesterol, HDL, LDL, cortisol, haptoglobin, IGG, and epinephrine. There was a significant
increase in RBCs, Hb, HDL, SOD, GSH, and IGG while a decrease in MDA, cholesterol, and LDL following GABA
supplementation. In conclusion, GABA had a beneficial effect on blood picture, differential leucocytic count, antioxidant
parameters, IGG, and haptoglobin.
parameters in laying hens. Sixty Lohmann Brown laying hens (32 weeks old) were randomly allotted to 3 groups (each
20) and given the medications daily for 4 weeks in drinking water. The groups were; control (without drug), GABA (40
mg/kg b.wt) and GABA (80 mg/kg b.wt). Layers were estimated to complete blood picture, Hb, differential leucocytic
count, antioxidant parameters, cholesterol, HDL, LDL, cortisol, haptoglobin, IGG, and epinephrine. There was a significant
increase in RBCs, Hb, HDL, SOD, GSH, and IGG while a decrease in MDA, cholesterol, and LDL following GABA
supplementation. In conclusion, GABA had a beneficial effect on blood picture, differential leucocytic count, antioxidant
parameters, IGG, and haptoglobin.