Staff Members - Benha University
Evaluation of serum chromogranin A as a useful tumor marker for diagnosis of hepatocellular carcinoma
• 2011
Publication Information
Authors
Ahmed M Awadallah, Hesham Ali Issa, Mohamed S Soliman
Keywords
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Journal
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Publisher
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Volume
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Issue
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Pages
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Background: In Egypt, HCC was reported to account for about 4.7% of chronic liver
disease patients. Approximately 80% of HCCs are associated with cirrhosis, which is
regarded as the most important precancerous etiological factor. Chromogranin A is a cellular
marker for neuroendocrine tumors. High serum levels of CgA have also been demonstrated
in patients with other malignancies including colon, lung, breast and prostate cancer.
Objective: To evaluate serum CgA as a marker for HCC. Patients and Methods: Eighty .
disease patients. Approximately 80% of HCCs are associated with cirrhosis, which is
regarded as the most important precancerous etiological factor. Chromogranin A is a cellular
marker for neuroendocrine tumors. High serum levels of CgA have also been demonstrated
in patients with other malignancies including colon, lung, breast and prostate cancer.
Objective: To evaluate serum CgA as a marker for HCC. Patients and Methods: Eighty .