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Prolongation of Corrected QT Interval in Diabetic Patients with Ketoacidosis

The Egyptian Journal of Hospital Medicine • 2022
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Publication Information
Authors Ahmed M, Hussein; Hala Abdel Moniem; Ahmed Bendary; Amira K. El-Alfy
Keywords Prolongation, QT Interval, Diabetes mellitus, Ketoacidosis
Journal The Egyptian Journal of Hospital Medicine
Publisher Egyptian Knowledge Bank
Volume 86
Issue Not Available
Pages 555-560
publication.type Local
Paper Link Open Link
Supplementary Materials Not Available
Abstract
Background: Diabetic ketoacidosis (DKA) is the most common acute hyperglycemic complication of diabetes.
According to a recent report DKA affects approximately 8 per 1000 diabetics annually. It is associated with significant
morbidity and mortality, with a worldwide mortality rate of 2-10%.
Objective: The aim of the work was to assessment of QTc interval prolongation among patients with DKA.
Patients and Methods: This prospective observational cohort study included 100 patients who were diagnosed with
DKA. The mean age of patients was 37.29±11.63 years, and 53% of them were males. All patients were subjected to
detailed history taking, full clinical examination, laboratory investigations and 12-lead ECG.
Results: Frequency of Prolonged QTmaxc amongst studied patients was 59%. Mean QTmaxc declined significantly
after treatment to be 414.6±44.1ms compared to 482.45±63.56ms before treatment with p