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Combined letrozole with clomiphene citrate versus letrozole only in induction of ovulation in polycystic ovary syndrome patients (A Randomized controlled trial)

• 2022
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Publication Information
Authors Ali Mahmoud Kotb El-Gazzar, Aziza Ali Negm, Ahmed Samy Saad,
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publication.type Local
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Abstract
Objective: to compare adding clomiphene citrate to letrozole in comparison with letrozole only Patients and method
: A total of 64 infertile woman with PCOS were assessed in
this randomized controlled trial in Department of Obstetrics and Gynecology at Imbaba General hospital and Banha
university hospital .
Results: The serum pregnancy test was positive in only
(6,3%) group A who receive letrazole alone while shows
(12.5%) in group B who took combined therapy with no
significance in P value(0.39) so group B shows higher pregnancy rates, The six weeks pulsations shows higher percentages in group B (9.4%) in compare to Group A (3.1%)
with P value of (0.3) , There is good significance in the
number of follicles (with P value 0.006) with appearance
of one follicle in group B was higher than group A (68.8%
in group B versus 37.5% in group A) ,Also the appearance
of 2 mature follicles happen only in group B (6.3%). the
follicular size appeared significance with P value (