Assesment of IgG&IgM,ELISA and IFAT in diagnosis of toxoplasmosis in risky pregnancies. J.Egypt.Soc.Parasitol., 20(2):817-820.
• 1990
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Authors
T.Gagar, A.F.El Fakahany
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Abstract
This study was carried out on 100 pregnant cases, divided into 5 groups of patients having congenitally malformed newborns, suffer ing from stillbirths, premature labours, repeated abortions and control group ‘the incidence of positive Toxoplasma antibodies was higher in the congenital malformation and stillbirths groups than other groups. Analysis of the results, showed that an excellent correlation exists between ELISA and IFAT with a minimal differences (< %).
INTRODUCTION
The diagnosis of toxoplasmosis is frequently dependent upon Serological data, Since clinical manifestation of the disease often mimic those of other diseases and the isolation of the parasite from patients is usually difficult. The most serological test used for diagnosis is the enzyme linked immunosorbent assay (ELISA). ELISA is rapidly gaining favour in the serodiagnosis of several parasitic infections (Voller et al., 1976) and is currently used for both the direct and indirect detection of toxoplasmosis (Araujo and Remington, 1980).
The aim of the present work is to make a correlation between ELISA and IFAT in the diagnosis of toxoplasmosis.
INTRODUCTION
The diagnosis of toxoplasmosis is frequently dependent upon Serological data, Since clinical manifestation of the disease often mimic those of other diseases and the isolation of the parasite from patients is usually difficult. The most serological test used for diagnosis is the enzyme linked immunosorbent assay (ELISA). ELISA is rapidly gaining favour in the serodiagnosis of several parasitic infections (Voller et al., 1976) and is currently used for both the direct and indirect detection of toxoplasmosis (Araujo and Remington, 1980).
The aim of the present work is to make a correlation between ELISA and IFAT in the diagnosis of toxoplasmosis.
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