Biochemical and Molecular Studies on the Protective Effect of Some Natural Antioxidants Supplementation on Experimentally-Induced Hyperuricemia and Renal Injury in Rats
Research Journal of Pharmaceutical, Biological and Chemical Sciences • 2016
Publication Information
Authors
Eman M. Fayad, Alshaimaa M. Said, and Hala M. Abo-Dief.
Keywords
Herbal plants – antioxidants- Biochemical effects- molecular effects
Journal
Research Journal of Pharmaceutical, Biological and Chemical Sciences
Publisher
Not Available
Volume
7
Issue
2
Pages
1201-1208
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Hyperuricemia is a level of uric acid in the blood that is abnormally high. In humans, the upper end of the normal range is 360 μmol/L (6 mg/dL) for women and 400 μmol/L (6.8 mg/dL) for men. Many factors contribute to hyperuricemia, including: genetics, insulin resistance, hypertension, renal insufficiency, obesity, diet, use of diuretics, and consumption of alcoholic beverages .Causes of hyperuricemia can be classified into three functional types: increased production of uric acid, decreased excretion of uric acid, and mixed type. Some plants widely used as dietary flavours such as ginger, radish and onion can be used as treatment against development of hyperuricaemia and that is the aim of this project.
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