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Molecular characterization of the equine herpesvirus 1 strains RacL11 and Kentucky D.

J Vet Med Sci. • 2007
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Publication Information
Authors Yasser M Ghanem, El-Sayed M Ibrahim, Souichi Yamada, Tomio Matsumura, Nikolaus Osterrieder, Tsuyoshi Yamaguchi, Hideto Fukushi
Keywords Not Available
Journal J Vet Med Sci.
Publisher Not Available
Volume 69
Issue 5
Pages 573-576
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
The pathogenicities of RacL11 and Kentucky D strains of equine herpesvirus 1 in the
hamster infection model are different from those of Ab4p and the Japanese isolates. Virus
genome restriction fragment length polymorphism analysis and sequence comparison of an
intergenic region, glycoproteins and tegument genes showed higher conservation but with
some strain-specific differences. These results indicate that point nucleotide differences in
RacL11 and Kentucky D might be responsible for their pathogenicity in rodent models.