Spectrophotometric determination of zinc in pharmaceutical samples with some salicylic azo compounds.
• 1994
Publication Information
Authors
Alaa S. Amin.
Keywords
Not Available
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
A sensitive spectrophotometric method for zinc has been established by reacting zinc with three salicylic acid azo dyes 2-hydroxy (Ia), 2-carboxy (Ib) and 4-(2-arsonophenylazo) salicylic acid (Ic) in universal buffer solution of pH 8.4, 7.1 and 6.0 respectively. The molar absorptivities are 1.16, 1.39 and 1.36 X 10 1/mol.cm at 515, 450 and 525 nm using reagents Ia, Ib and Ic respectively. The formed complexes have the molar ratios of zinc to ligands 1: 1 and 2: 1. Beer's law is obeyed upto 7.19 ppm of zinc whereas the optimum concentration range as evaluated by Ringbom's method is 0.5-7.00 ppm. Sandell sensitivities of the method are evaluated. The method has been used to determine zinc in various pharmaceutical products.
Staff Members - Benha University