The aim of this study was to investigate the different forms of urinary tract affections in dogs and cats by using ultrasonography. The present study was carried out on 118 clinical cases (27 dogs and 91 cats) of both sexes (90 males and 28 females) and different ages (ranged from one to 14 years old) suffered from urinary tract affections. The recorded cases were urolithiasis (n= 42), chronic cystitis (n= 41), hemorrhagic cystitis (n= 20), uroabdomen (n= 4), polycystic kidney (n= 8), renal abscess (n= 1), renal mass (n= 1), and urinary bladder mass (n= 1). The results revealed that in cats, urolithiasis represented the highest percentage among recorded cases (34.00%), followed by chronic cystitis (30.70%), with minor prevalence of renal mass, renal abscess, and urinary bladder mass (1.09% each). Whereas in dogs, the highest percentage of cases were chronic cystitis (48.10%), followed by urolithiasis (40.70%), with minor prevalence of uroabdomen (3.70%). The ultrasonographic investigations revealed that urolithiasis appeared as a hyperechoic structure with a distal acoustic shadowing, while the key feature for the chronic cystitis was the notable thick and corrugated urinary bladder wall. The present study concluded that ultrasonography was beneficial for the diagnosis of the different clinical affections of urinary tract in dogs and cats.