Background: To date, online learning has received considerable attention as a mean of providing alternatives to traditional instructor-led education and it is expected to continue to hold a major place in higher education institutions. The study aimed to determine the effectiveness of implementing an online educational program about head nurse role at Benha University Hospital. The included subjects were all available Benha Faculty nursing interns who enrolled in 2015/2016 internship year at Benha University Hospital, their number were 39. Four tools were used for data collection; Knowledge, Technological skills, Attitude and Evaluation questionnaire sheets. The study results revealed; firstly, implementing the online educational program about head nurse role was effective i.e. there was a general improvement in nursing interns' knowledge about head nurse roles, technological skills, attitude toward online learning after implementing the online program, secondly, nursing interns had a positive attitude to online learning and thirdly, the highest percent of nursing–interns rated the program as “a good level” through their evaluation at post program and follow up phases. The study recommended, integration of online learning into teaching plans for various study stages, and conducting continuous training programs for teaching staff members about online learning design and implementation by experts in this field.