As it permits both vessel luminal evaluation and plaque identification, multi-detector CT
angiography has assumed a prominent position in early diagnosis of coronary artery disease
(CAD). The purpose of this research was to evaluate the association between epicardial
adipose tissue density and coronary artery disease prevalence and location. In accordance
with the atherosclerotic cardiovascular disease (ASCVD) recommendations of the
American Heart Association and the American College of Cardiology (AHA/ACC), a
cross-sectional research was conducted on 50 individuals at high risk of CAD. Patients had
a thorough history and physical examination as well as laboratory tests (serum creatinine,
estimated glomerular filtration rate, and MDCT angiography). There were statistically
significant differences between the two groups in proximal LCX, distal LAD, and distal
LCX. Proximal RCA, proximal LCX, middle LCX, distal RCA, and distal LAD all differed
significantly by severity group. Both the proximal LCX (r= 0.286, P=0.044) and the distal
LAD (r= 0.554, P0.001) were positively correlated with Severity of Coronary Artery,
whereas the intermediate LAD (r= -0.322, P=0.022) was negatively correlated with
Severity of Coronary Artery. In conclusion, the present research found that peri-coronary
epicardial fat density is substantially related to the existence and severity of coronary artery
disease. Significant positive correlations were found between Severity of Coronary Artery
and both the proximal LCX and the distal LAD, whereas substantial negative correlations
were found between Severity of Coronary Artery and the intermediate LAD.
Epicardial adipose tissue density; cardiac computed tomography; coronary artery disease;
cardiomyopathy; coronary artery disease.