Heart failure is a major health problem in which reduced functional capacity, exercise tolerance, and quality of life are the most basic findings. Despite improvements in diagnosis and treatment; it is associated with high morbidity and mortality.
According to the American College of Cardiology& American Heart Association practice guidelines, echocardiography is “the single most useful test in the evaluation of patients with heart failure (HF), it offers the ability to assess chamber size, shape, and function, filling pressures, pulmonary artery pressure, valvular disease, congenital abnormalities, and restrictive physiology .
Despite its obvious clinical utility, it is difficult to demonstrate that echocardiography influences patient outcomes or predicts response to specific therapy. Although numerous variables can be measured echocardiographically, it is not clear which of these variables predicts outcome in HF.
Various markers of left ventricular (LV) systolic and diastolic function derived from Doppler echocardiography have been used to predict functional capacity, including LV cavity dimension, ejection fraction, and transmitral inflow velocity.
TDI is a new echocardiography technique that enables the evaluation of left ventricular function by the analysis of systolic and diastolic myocardial velocities obtained from mitral annulus but there are few data on the correlation of TDI variables with clinical feature in patients with LV dysfunction.
The aim of this study was to determine echocardiographic predictors of outcome in patients with advanced heart failure (HF) due to severe left ventricular (LV) systolic dysfunction.
This study was carried out on one hundred patients from the attendant of cardiology department in Benha university hospital, presented with heart failure and their left ventricular ejection fraction (LVEF) ≤ 35% .