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Investigating the potential link between seroprevalence of Toxoplasma IgG and both types of diabetes mellitus in Benha city, Egypt

• 2022
العودة
معلومات البحث
المؤلفون Asmaa A Elkholy1, Rabab E Omar1, Ayman M Elbadawy2, Mona A Elawady3, Eman Abou-Ouf1
الكلمات المفتاحية Not Available
المجلة العلمية Not Available
الناشر Not Available
المجلد Not Available
العدد Not Available
الصفحات Not Available
publication.type International
رابط البحث Not Available
المواد المرفقة Not Available
الملخص
Background: In immunocompromised individuals, e.g. diabetics, toxoplasmosis is one of the significant
opportunistic illnesses. The sensitivity and susceptibility to infections increases in diabetic patients
causing severe health consequences unless diagnosed and treated early.
Objective: The study was performed to detect the possible association between toxoplasmosis and both
types of diabetes mellitus linked with glycated hemoglobin (HbA1c) levels.
Patients and Methods: The study included 180 serum samples, 90 from diabetic patients and 90 healthy
controls. Diabetic cases were divided into 22 diagnosed as type 1 diabetes (T1DM) and 68 type 2 diabetes
(T2DM). Sera were tested for Toxoplasma IgG antibodies using ELISA technique, and HbA1c levels were
estimated in all diabetic patients.
Results: Toxoplasma IgG seropositivity was recorded in 67/90 (74.4%) of diabetic patients and 30/90
(33.3%) of the controls with statistically significant difference (P