أعضاء هيئة التدريس - جامعة بنها
Genetic Variations in the Growth Arrest–Specific 6 (GAS6) Protein Gene in Patients with Acute Coronary Syndrome
• 2015
معلومات البحث
المؤلفون
Mohamed Mohamed Elshafey MD , Jehan Hassan Sabry MD , Omnia El
Saeed Abdlla MD and Rania Fouad Abdel Ghany M.B.B.Ch .
الكلمات المفتاحية
Not Available
المجلة العلمية
Not Available
الناشر
Not Available
المجلد
Not Available
العدد
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الصفحات
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publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Growth arrest–specific gene 6 (GAS6) encodes a vitamin K–
dependent protein that regulates inflammation, angiogenesis, and
atherosclerotic plaque formation. The level of GAS6 expression is
associated with plaque stability and stroke. The role of GAS6 in
cardiovascular disease, particularly in acute coronary syndrome (ACS)
was explored .The study investigated the role of the single nucleotide
polymorphism (c.834+7G>A) of GAS6 in ACS. The genotype
frequencies for GG, AG, and AA, respectively, in patients with ACS
were 57.1% (16/28), 28.6% (8/28), and 14.3% (4/28) and were 20%
(4/20), 40% (8/20), 40% (8/20) in the control group. The AA genotype
and A allele were less frequent in patients with ACS than in control
subjects (P
dependent protein that regulates inflammation, angiogenesis, and
atherosclerotic plaque formation. The level of GAS6 expression is
associated with plaque stability and stroke. The role of GAS6 in
cardiovascular disease, particularly in acute coronary syndrome (ACS)
was explored .The study investigated the role of the single nucleotide
polymorphism (c.834+7G>A) of GAS6 in ACS. The genotype
frequencies for GG, AG, and AA, respectively, in patients with ACS
were 57.1% (16/28), 28.6% (8/28), and 14.3% (4/28) and were 20%
(4/20), 40% (8/20), 40% (8/20) in the control group. The AA genotype
and A allele were less frequent in patients with ACS than in control
subjects (P