أعضاء هيئة التدريس - جامعة بنها
The relation between vitamin D level and increased risk for early-onset neonatal sepsis in full-term infants
Medical Research Journal • 2016
معلومات البحث
المؤلفون
Mohamed S. Seliema, Omima M. Abdel Haiea, Amira I. Mansourb
and Soad Said Mohamed Elsayed Salamaa
الكلمات المفتاحية
early-onset sepsis, late-onset sepsis, neonatal sepsis, vitamin D
المجلة العلمية
Medical Research Journal
الناشر
Not Available
المجلد
Not Available
العدد
Not Available
الصفحات
Not Available
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Objectives The aim of the study was to determine the role
of maternal and neonatal plasma vitamin D levels in earlyonset
sepsis (EOS) and in its severity in term infants.
Methods This study was performed on 60 neonates and
their mothers who were divided into two groups. Group 1
comprised 30 full-term neonates with EOS. Group 2
comprised 30 healthy neonates of matched age and sex
who served as the control group. All participants were
subjected to the following investigations: complete blood
count, C-reactive protein, blood culture and serum vitamin
D levels in both neonates and their mothers.
Results Maternal and neonatal vitamin D levels were lower
in the study group compared with the control group and
their levels were significantly higher in the summer season.
We found a significant negative correlation between infant
vitamin D level and C-reactive protein in the patient group.
In contrast, there was a significant positive correlation
between maternal and neonatal vitamin D levels in both
groups. The best cutoff value of neonatal vitamin D for the
risk of sepsis was 14.4 ng.
Conclusion Lower maternal and neonatal vitamin D levels
are associated with EOS. However, there was no significant
relation between vitamin D deficiency and outcome. Med
Res J 15:16–21 c 2016 Medical Research Journal.
Medical Research Journal 2016, 15:16–21
of maternal and neonatal plasma vitamin D levels in earlyonset
sepsis (EOS) and in its severity in term infants.
Methods This study was performed on 60 neonates and
their mothers who were divided into two groups. Group 1
comprised 30 full-term neonates with EOS. Group 2
comprised 30 healthy neonates of matched age and sex
who served as the control group. All participants were
subjected to the following investigations: complete blood
count, C-reactive protein, blood culture and serum vitamin
D levels in both neonates and their mothers.
Results Maternal and neonatal vitamin D levels were lower
in the study group compared with the control group and
their levels were significantly higher in the summer season.
We found a significant negative correlation between infant
vitamin D level and C-reactive protein in the patient group.
In contrast, there was a significant positive correlation
between maternal and neonatal vitamin D levels in both
groups. The best cutoff value of neonatal vitamin D for the
risk of sepsis was 14.4 ng.
Conclusion Lower maternal and neonatal vitamin D levels
are associated with EOS. However, there was no significant
relation between vitamin D deficiency and outcome. Med
Res J 15:16–21 c 2016 Medical Research Journal.
Medical Research Journal 2016, 15:16–21