أعضاء هيئة التدريس - جامعة بنها
Regioselective synthesis, antitumor and antioxidant activities of some 1,2,4-triazole derivatives based on 4-phenyl-5-(quinolin-8- yloxy)methyl-4H-1,2,4-triazole-3-thiol
PHOSPHORUS, SULFUR, AND SILICON • 2016
معلومات البحث
المؤلفون
M. S. Behalo, M. S. Amine & I. M. Fouda
الكلمات المفتاحية
Quinoline; triazole; pyrazole;
thiazole; antitumor;
antioxidant
المجلة العلمية
PHOSPHORUS, SULFUR, AND SILICON
الناشر
Taylor, Francis
المجلد
Not Available
العدد
Not Available
الصفحات
Not Available
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Regioselective synthesis of sometriazole derivatives 4–18 was achieved fromthe versatile, readily accessible
4-phenyl-5-(quinolin-8-yloxy)methyl-4H-1,2,4-triazole-3-thiol/thione 3. The structures of the newly synthesized
products were confirmed and characterized by IR, 1H NMR, 13C NMR, and mass spectral studies. Most
of the synthesized compounds were evaluated for their antitumor and antioxidant activities and demonstrated
potent to weak activities.
4-phenyl-5-(quinolin-8-yloxy)methyl-4H-1,2,4-triazole-3-thiol/thione 3. The structures of the newly synthesized
products were confirmed and characterized by IR, 1H NMR, 13C NMR, and mass spectral studies. Most
of the synthesized compounds were evaluated for their antitumor and antioxidant activities and demonstrated
potent to weak activities.