Ear infections (particularly, otitis media) is a prevailing and common infection in developing countries
causing local damage and threatening complications. Pseudomonas aeruginosa is the most common
pathogen causing chronic suppurative otitis media (CSOM) and malignant otitis externa. The objective
of this study is to identify incidence of Pseudomonas aeruginosa involved in ear infections and
associated biochemical parameters which may be changed. External auditory canal in rabbit ears was
inoculated with (106
) colony-forming units (CFU) of Pseudomonas aeruginosa or left as sterile controls
for eight weeks. There are significantly decrease results at (P