FAECAL AND JEJUNAL BACTERIAL FLORA IN
IRRITABLE BOWEL SYNDROME WITH INCOMPETENT
ILEOCAECAL VALVE
By
* **
Mohamed A. Moussa MD , Laila A. Soliman MD ,, Nabil A. Khattab MD,
Yehia Saddik MD, Mohamed Salem MD, Alaa Ibrahim MD, and
Mohamed Shawki MD
From
Departments of Internal Medicine Ain Shams, Benha Faculties of
Medicine and Bacteriology Department Ain Shams Faculty of
** Medicine
ABSTRACT
The aim of this work was to study the jejunal and faecal
flora in irritable bowel syndrome (IBS) patients with and without
ileocaecal valve incompetence to assess the qualitative and
quantitative incidence of different bacterial species both
aerobically and anaerobically. This study was carried on 25 IBS
patients with incompetent ileocaecal valve and another 25
patients with competent valve. Bacteriological examination of the
jejunal aspirates and faecal samples of both groups, showed raised
figures as regards all types and species of organisms studied.
Irritable bowel syndrome patients with ileocaecal valve
incompetence showed higher significant bacteriological counts,
especially in jejunal aspirates. The pattern of abnormal jejunal
flora detected in patients with incompetent valve pointed to
colonic origin. Therefore such IBS patients with ileocaecal valve
incompetence may get benefit from some bacteriostatic agents
especially those affecting the anaerobes in a trial to correct the
associated floral alterations and overgrowth together with
motility modifying drugs as domperidone.