أعضاء هيئة التدريس - جامعة بنها
Effect of ceftriaxone on blood pressure, respiration and its analgesic and antipyretic activities.
Eurasian Journal of Veterinary Sciences. 2012, 28(1): 41-46. • 2012
معلومات البحث
المؤلفون
Aboubakr M, Elsayed M and Elkomy A.
الكلمات المفتاحية
ceftriaxone, analgesic. antipyretic
المجلة العلمية
Eurasian Journal of Veterinary Sciences. 2012, 28(1): 41-46.
الناشر
Not Available
المجلد
28
العدد
1
الصفحات
41-46
publication.type
International
رابط البحث
Open Link
المواد المرفقة
Not Available
الملخص
Aim: The aim of this study was to determine the effect of ceftriaxone on blood pressure and respiration in dog. In addition, analgesic and antipyretic activities of ceftriaxone were investigated in mice and rats.
Materials and Methods: Effect of different doses of ceftriaxone (26.66, 53.33, 106.66 mg/kg, IV) on blood pressure and respiration rate were determined in anesthetized dogs. Analgesic and antipyretic activities of two different doses of ceftriaxone were investigated in mice and rats, respectively.
Results: Ceftriaxone had no effect on blood pressure and rate of respiration in anesthetized dogs. However, ceftriaxone (260 and 520 mg/kg) had a significant analgesic effect for four hours and had a significant antipyretic effect at 2.5 and 1.5 hours at doses of 180 and 360 mg/kg, respectively.
Conclusion: Ceftriaxone is preferable in bacterial infections or feverish conditions owing to its antibacterial, antipyretic and analgesic activities.
Materials and Methods: Effect of different doses of ceftriaxone (26.66, 53.33, 106.66 mg/kg, IV) on blood pressure and respiration rate were determined in anesthetized dogs. Analgesic and antipyretic activities of two different doses of ceftriaxone were investigated in mice and rats, respectively.
Results: Ceftriaxone had no effect on blood pressure and rate of respiration in anesthetized dogs. However, ceftriaxone (260 and 520 mg/kg) had a significant analgesic effect for four hours and had a significant antipyretic effect at 2.5 and 1.5 hours at doses of 180 and 360 mg/kg, respectively.
Conclusion: Ceftriaxone is preferable in bacterial infections or feverish conditions owing to its antibacterial, antipyretic and analgesic activities.