Miscarriage is the spontaneous loss of a fetus before it is viable, occurring at a rate of 15–20%. Recurrent spontaneous abortion (RSA) or habitual miscarriage is defined as repeated occurrence of 3 or more miscarriages before 20th week of gestation accounting for the most common complication of early pregnancy in humans. Various etiological factors responsible for recurrent miscarriage are anatomical, genetical, endocrinological, immunological, and infectious. The endocrinological abnormalities may be polycystic ovarian syndrome, hyperprolactinemia, luteal phase defect, thyroid dysfunction, diabetes, or hyperandrogenism contributing to recurrent pregnancy loss.In this thesis we will review the relation between maternal thyoid function and uterine artery doppler in women with recurrent unexplained pregnancy loss.
Patients and methods
Case group:50 nonpregnant women with history of 3 or more misscariages had thyroid function tested and uterine artery Doppler measurements.
Control group:50 nonpregnant women with history of at least one healthy pregnancy had thyoid function tested and uterine artery Doppler measurements.
Results
A strong relation was found between thyroid dysfunction and recurrent miscarriage. A strong relation relation was found between uterine a. Doppler and recurrent miscarriage.
Conclusion
Hence it is advisable to suggest to the pregnant women to go in for thyroid testing as soon as possible after knowing they are pregnant.
More studies with larger sample sizes are needed to detect subclinical thyroid dysfunction and thus obtaining more accurate results.