BACKGROUND: The aim of this study is to compare results of wound healing following harvesting the long saphenous vein from the lower limb in two group from below and above knee in patients undergoing coronary artery bypass surgery. Methods: From January 2011 till February 2012, a total of 120 patients were prepared to undergo CABG procedure susing internal thoracic artery as a graft in all the cases in addition to saphenous vein. Patients were divided into 2 groups first group include 60 patient underwent CABG with harvesting the long saphenous vein entirely from one leg with extension of the leg incision above the knee, the second group also included 60CABG with harvesting the long saphenous vein from both legs without extensionof the leg incision above the knee. Our limit was the upper border of the patella. Results:The wounds were assessed daily using the ASEPSISscoring system. In group A, significantly more patients (25%)had an ASEPSIS score > 10, compared to group B (5%). The mean ASEPSIS score was significantly lower in groupB than groups A. Conclusion: The ASEPSIS score is reduced when the saphenous vein harvesting was restricted to below knee level.