Fasting serum lipid, lipoprotein and apoHpopthe mean of HDL-cholesterol was significantly rotrin profiles were determined in 20 women using lower in the combined oral contraceptive than the a Progestin only -injectable contraceptive (DepoDMPA
group. No significant difference was noted Jll'(Wi!ra) for long term duration (3 -6 years). The
in the means of apolipoprotein AI/ apolipoprotein
fiwIin~ were compared with that of long term All and apolipoporotein AI/ apolipoprotein B betIIIttS
of low dose combined oral contraceptive ween the study groups and the controls.
(Nordette) and appropriately matched controls to
It is concluded that the long ferm usc of ~the risk of atherosclerosis after long 1~rm steroidal contraceptives is associated with alte
~Q( steroidal contraceptives using recent cardio· rations in lipid and apolipoprotein pwfiles that
ascnJ.ar disease risk indices.