Engineers have spent more time and effort in understanding local scour phenomena, especially engineers involved in bridge foundation design. Estimating local scour depth, dS values are important in order to avoid catastrophic failure of bridges and to get more economical design. Local scour around exposed piles using 3D computational fluid dynamic model was not studied extensively by researchers, where most of researchers concentrated on prediction of single pile scour and limited flow conditions. The main objective of this paper is to use the SSIIM model in predicting local scour around pile group consisting of two circular piles under different flow conditions and to produce more-reliable equations to predict pile group scour precisely. Results and the developed equations by SSIIM model show the influence of different parameters on the local scour around the pile group consisting of two piles. The results of the SSIIM model runs were analyzed in the light of pervious works and developed useful curves and equations to calculate the local scour around pile group consisting of two piles for different conditions.